EUvsVirus Hackathon

The European Commission, led by the European Innovation Council and in close collaboration with the EU member states, will host a pan-European hackathon to connect civil society, innovators, partners and investors across Europe in order to develop innovative solutions for coronavirus-related challenges. Now is your chance to help tackle coronavirus! When? 24, 25 and 26…

When Would Immunologists Consider a Nanomaterial to be Safe? Recommendations for Planning Studies on Nanosafety

Abstract The immune system is professional in recognizing and responding to non‐self, including nanomaterials. Immune responses by professional and nonprofessional immune cells are thus nearly inevitable upon exposure of cells and organisms to such materials. The state of research into taking the immune system into account in nanosafety studies is reviewed and three aspects in…

Driving the nanoinformatics wave

The NanoCommons (https://www.nanocommons.eu/) research e-infrastructure and NanoSolveIT (https://nanosolveit.eu/) projects are developing the knowledge management and nanoinformatics tools to support in silico nanosafety assessment  (published in Scitech Europa www.scitecheuropa.eu) DOI: http://doi.org/10.5281/zenodo.3765525 You can access the article here.

Zeta‐Potential Read‐Across Model Utilizing Nanodescriptors Extracted via the NanoXtract Image Analysis Tool Available on the Enalos Nanoinformatics Cloud Platform

Abstract Zeta potential is one of the most critical properties of nanomaterials (NMs) which provides an estimation of the surface charge, and therefore electrostatic stability in medium and, in practical terms, influences the NM’s tendency to form agglomerates and to interact with cellular membranes. This paper describes a robust and accurate read‐across model to predict…

JRC Workshop on Safe and Sustainable Smart Nanomaterials

The European Commission’s Joint Research Centre (JRC) and the Directorate-General for Research and Innovation (RTD) will jointly organise a Workshop on Safe and Sustainable Smart Nanomaterials in Ispra (Italy) on 24-25 March 2020. The workshop is focused on smart (responsive, multi-functional) nanomaterials, as such or embedded in products, which are developed for application in industrial sectors such…

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D

Abstract Protein-protein-interaction networks (PPINs) organize fundamental biological processes, but how oncogenic mutations impact these interactions and their functions at a network-level scale is poorly understood. Here, we analyze how a common oncogenic KRAS mutation (KRASG13D) affects PPIN structure and function of the Epidermal Growth Factor Receptor (EGFR) network in colorectal cancer (CRC) cells. Mapping >6000…

D10.3 – Initial version of NanoCommons Sustainability Plan

The NanoCommons deliverable “D10.3 – Initial version of NanoCommons Sustainability Plan” is now available to view online. The report is available under the Creative Commons Attribution 4.0 International Licence (CC BY 4.0). During the first year of the project a strategy was developed for ensuring sustainability of the NanoCommons research infrastructure and including the tools and services…

D10.2 – Interactions Needs and Goals of Nano Safety Projects and Programs

The updated NanoCommons deliverable “D10.2 – Interactions Needs and Goals of Nano Safety Projects and Programs” is now available to view online. The report is available under the Creative Commons Attribution 4.0 International Licence (CC BY 4.0). The Horizon 2020 (H2020) project NanoCommons is establishing a long-term infrastructure to benefit nanotechnology and nanosafety research. This means that…