An Integrative Computational Approach for a Prioritization of Key Transcription Regulators Associated With Nanomaterial-Induced Toxicity

Publications

Abstract A rapid increase of new nanomaterial (NM) products poses new challenges for their risk assessment. Current traditional methods for estimating potential adverse health effect of NMs are complex, time consuming, and expensive. In order to develop new prediction tests for nanotoxicity evaluation, a systems biology approach, and data from high-throughput omics experiments can be…

Read-across predictions of nanoparticle hazard endpoints: a mathematical optimization approach

Outputs, Outputs, Publications

NanoCommons supported paper: Read-across predictions of nanoparticle hazard endpoints: a mathematical optimization approach Abstract In the present study, a novel read-across methodology for the prediction of toxicity related end-points of engineered nanomaterials (ENMs) is developed. The proposed method lies in the interface between the two main read-across approaches, namely the analogue and the grouping methods,…

European Registry of Materials Hackathon – Oral Presentation

Oral Presentations, Outputs

  Egon Willighagen from the University of Maastricht has given a presentation on the need for FAIR (Findable, Accessible, Interoperable and Reusable) identifiers for nanomaterials used in nanosafety, nanomedicine and nanotechnology research. The presentation was given during the 4th NanoCommons General Assembly that took place in Limassol, Cyprus in July 2019. The presentation is available…